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Therapeutic Strategy for the Prevention of Pseudorabies Virus Infection in C57BL/6 Mice by 3D8 scFv with Intrinsic Nuclease Activity

3D8 single chain variable fragment (scFv) is a recombinant monoclonal antibody with nuclease activity that was originally isolated from autoimmune-prone MRL mice. In a previous study, we analyzed the nuclease activity of 3D8 scFv and determined that a HeLa cell line expressing 3D8 scFv conferred res...

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Detalles Bibliográficos
Autores principales: Lee, Gunsup, Cho, SeungChan, Hoang, Phuong Mai, Kim, Dongjun, Lee, Yongjun, Kil, Eui-Joon, Byun, Sung-June, Lee, Taek-Kyun, Kim, Dae-Hyun, Kim, Sunghan, Lee, Sukchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588720/
https://www.ncbi.nlm.nih.gov/pubmed/26255831
http://dx.doi.org/10.14348/molcells.2015.0073