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Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome
Background: The manipulation of pregnancy diets in animals can lead to changes in DNA methylation with phenotypic consequences in the offspring. Human studies have concentrated on the effects of nutrition during early gestation. Lacking in humans is an epigenome-wide association study of DNA methyla...
Autores principales: | Tobi, Elmar W, Slieker, Roderick C, Stein, Aryeh D, Suchiman, H Eka D, Slagboom, P Eline, van Zwet, Erik W, Heijmans, Bastiaan T, Lumey, LH |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588866/ https://www.ncbi.nlm.nih.gov/pubmed/25944819 http://dx.doi.org/10.1093/ije/dyv043 |
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