Pre-differentiation of human neural stem cells into GABAergic neurons prior to transplant results in greater repopulation of the damaged brain and accelerates functional recovery after transient ischemic stroke

INTRODUCTION: Despite attempts to prevent brain injury during the hyperacute phase of stroke, most sufferers end up with significant neuronal loss and functional deficits. The use of cell-based therapies to recover the injured brain offers new hope. In the current study, we employed human neural ste...

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Detalles Bibliográficos
Autores principales: Abeysinghe, Hima C. S., Bokhari, Laita, Quigley, Anita, Choolani, Mahesh, Chan, Jerry, Dusting, Gregory J., Crook, Jeremy M., Kobayashi, Nao R., Roulston, Carli L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588906/
https://www.ncbi.nlm.nih.gov/pubmed/26420220
http://dx.doi.org/10.1186/s13287-015-0175-1

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