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A rationally designed combined treatment with an alphavirus-based cancer vaccine, sunitinib and low-dose tumor irradiation completely blocks tumor development
The clinical efficacy of therapeutic cancer vaccines remains limited. For effective immunotherapeutic responses in cancer patients, multimodal approaches capable of both inducing antitumor immune responses and bypassing tumor-mediated immune escape seem essential. Here, we report on a combination th...
Autores principales: | Draghiciu, Oana, Boerma, Annemarie, Hoogeboom, Baukje Nynke, Nijman, Hans W, Daemen, Toos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589062/ https://www.ncbi.nlm.nih.gov/pubmed/26451295 http://dx.doi.org/10.1080/2162402X.2015.1029699 |
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