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A rationally designed combined treatment with an alphavirus-based cancer vaccine, sunitinib and low-dose tumor irradiation completely blocks tumor development

The clinical efficacy of therapeutic cancer vaccines remains limited. For effective immunotherapeutic responses in cancer patients, multimodal approaches capable of both inducing antitumor immune responses and bypassing tumor-mediated immune escape seem essential. Here, we report on a combination th...

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Detalles Bibliográficos
Autores principales: Draghiciu, Oana, Boerma, Annemarie, Hoogeboom, Baukje Nynke, Nijman, Hans W, Daemen, Toos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589062/
https://www.ncbi.nlm.nih.gov/pubmed/26451295
http://dx.doi.org/10.1080/2162402X.2015.1029699

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