Peripheral Blood Cells from Patients with Autoimmune Addison's Disease Poorly Respond to Interferons In Vitro, Despite Elevated Serum Levels of Interferon-Inducible Chemokines

Autoimmune Addison's disease (AAD) is a disorder caused by an immunological attack on the adrenal cortex. The interferon (IFN)-inducible chemokine CXCL10 is elevated in serum of AAD patients, suggesting a peripheral IFN signature. However, CXCL10 can also be induced in adrenocortical cells stim...

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Detalles Bibliográficos
Autores principales: Edvardsen, Kine, Bjånesøy, Trine, Hellesen, Alexander, Breivik, Lars, Bakke, Marit, Husebye, Eystein S., Bratland, Eirik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589105/
https://www.ncbi.nlm.nih.gov/pubmed/25978633
http://dx.doi.org/10.1089/jir.2014.0171

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