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Intratumor Heterogeneity of ALK-Rearrangements and Homogeneity of EGFR-Mutations in Mixed Lung Adenocarcinoma

BACKGROUND: Non Small Cell Lung Cancer is a highly heterogeneous tumor. Histologic intratumor heterogeneity could be ‘major’, characterized by a single tumor showing two different histologic types, and ‘minor’, due to at least 2 different growth patterns in the same tumor. Therefore, a morphological...

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Detalles Bibliográficos
Autores principales: Marino, Federica Zito, Liguori, Giuseppina, Aquino, Gabriella, La Mantia, Elvira, Bosari, Silvano, Ferrero, Stefano, Rosso, Lorenzo, Gaudioso, Gabriella, De Rosa, Nicla, Scrima, Marianna, Martucci, Nicola, La Rocca, Antonello, Normanno, Nicola, Morabito, Alessandro, Rocco, Gaetano, Botti, Gerardo, Franco, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589235/
https://www.ncbi.nlm.nih.gov/pubmed/26422230
http://dx.doi.org/10.1371/journal.pone.0139264