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Ammonia Affects Astroglial Proliferation in Culture
Primary cultures of rat astroglial cells were exposed to 1, 3 and 5 mM NH(4)Cl for up to 10 days. Dose- and time-dependent reductions in cell numbers were seen, plus an increase in the proportion of cells in the S phase. The DNA content was reduced in the treated cells, and BrdU incorporation dimini...
Autores principales: | Bodega, Guillermo, Segura, Berta, Ciordia, Sergio, Mena, María del Carmen, López-Fernández, Luis Andrés, García, María Isabel, Trabado, Isabel, Suárez, Isabel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589356/ https://www.ncbi.nlm.nih.gov/pubmed/26421615 http://dx.doi.org/10.1371/journal.pone.0139619 |
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