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Tissue-Specific Enrichment of Lymphoma Risk Loci in Regulatory Elements

Though numerous polymorphisms have been associated with risk of developing lymphoma, how these variants function to promote tumorigenesis is poorly understood. Here, we report that lymphoma risk SNPs, especially in the non-Hodgkin’s lymphoma subtype chronic lymphocytic leukemia, are significantly en...

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Detalles Bibliográficos
Autores principales: Hayes, James E., Trynka, Gosia, Vijai, Joseph, Offit, Kenneth, Raychaudhuri, Soumya, Klein, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589387/
https://www.ncbi.nlm.nih.gov/pubmed/26422229
http://dx.doi.org/10.1371/journal.pone.0139360