Conserved Motifs within Hepatitis C Virus Envelope (E2) RNA and Protein Independently Inhibit T Cell Activation

T cell receptor (TCR) signaling is required for T-cell activation, proliferation, differentiation, and effector function. Hepatitis C virus (HCV) infection is associated with impaired T-cell function leading to persistent viremia, delayed and inconsistent antibody responses, and mild immune dysfunct...

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Detalles Bibliográficos
Autores principales: Bhattarai, Nirjal, McLinden, James H., Xiang, Jinhua, Kaufman, Thomas M., Stapleton, Jack T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589396/
https://www.ncbi.nlm.nih.gov/pubmed/26421924
http://dx.doi.org/10.1371/journal.ppat.1005183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589396/
https://www.ncbi.nlm.nih.gov/pubmed/26421924
http://dx.doi.org/10.1371/journal.ppat.1005183

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