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Oseltamivir Resistance in Influenza A(H6N2) Caused by an R292K Substitution in Neuraminidase Is Not Maintained in Mallards without Drug Pressure

BACKGROUND: Wild waterfowl is the natural reservoir of influenza A virus (IAV); hosted viruses are very variable and provide a source for genetic segments which can reassort with poultry or mammalian adapted IAVs to generate novel species crossing viruses. Additionally, wild waterfowl act as a reser...

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Detalles Bibliográficos
Autores principales: Gillman, Anna, Muradrasoli, Shaman, Mårdnäs, Andreas, Söderström, Hanna, Fedorova, Ganna, Löwenthal, Max, Wille, Michelle, Daggfeldt, Annika, Järhult, Josef D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589409/
https://www.ncbi.nlm.nih.gov/pubmed/26422258
http://dx.doi.org/10.1371/journal.pone.0139415