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Antithrombin III/SerpinC1 insufficiency exacerbates renal ischemia/reperfusion injury
Antithrombin III, encoded by SerpinC1, is a major anti-coagulation molecule in vivo and has anti-inflammatory effects. We found that patients with low antithrombin III activities presented a higher risk of developing acute kidney injury after cardiac surgery. To study this further, we generated Serp...
Autores principales: | Wang, Feng, Zhang, Guangyuan, Lu, Zeyuan, Geurts, Aron M, Usa, Kristie, Jacob, Howard J, Cowley, Allen W, Wang, Niansong, Liang, Mingyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589441/ https://www.ncbi.nlm.nih.gov/pubmed/26108065 http://dx.doi.org/10.1038/ki.2015.176 |
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