Cargando…
Macrophage-derived Tumor Necrosis Factor-α mediates diabetic renal injury
Monocyte/macrophage recruitment correlates strongly with the progression of diabetic nephropathy. Tumor necrosis factor-alpha (TNF-α) is produced by monocytes/macrophages but the direct role of TNF-α and/or macrophage-derived TNF-α in the progression of diabetic nephropathy remains unclear. Here we...
Autores principales: | Awad, Alaa S., You, Hanning, Gao, Ting, Cooper, Timothy K., Nedospasov, Sergei A., Vacher, Jean, Wilkinson, Patrick F., Farrell, Francis X., Reeves, W. Brian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589442/ https://www.ncbi.nlm.nih.gov/pubmed/26061548 http://dx.doi.org/10.1038/ki.2015.162 |
Ejemplares similares
-
Arginase inhibition mediates renal tissue protection in diabetic nephropathy by a nitric oxide synthase 3-dependent mechanism
por: You, Hanning, et al.
Publicado: (2013) -
Delayed Treatment with a Small Pigment Epithelium Derived Factor (PEDF) Peptide Prevents the Progression of Diabetic Renal Injury
por: Awad, Alaa S., et al.
Publicado: (2015) -
Arginase-2 Mediates Diabetic Renal Injury
por: Morris, Sidney M., et al.
Publicado: (2011) -
Tumor necrosis factor-α induces renal vasoconstriction as well as natriuresis in mice
por: Shahid, Mohd, et al.
Publicado: (2008) -
Macropinocytosis of Extracellular Glutathione Ameliorates Tumor Necrosis Factor α Release in Activated Macrophages
por: Gould, Neal S., et al.
Publicado: (2011)