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Th-17 cell activation in response to high salt following acute kidney injury is associated with progressive fibrosis and attenuated by AT-1R antagonism

Exposure of rats to elevated dietary salt following recovery from acute kidney injury (AKI) accelerates the transition to chronic kidney disease (CKD), and is dependent on lymphocyte activity. Here we tested whether high salt diet triggers lymphocyte activation in post-ischemic kidneys to worsen ren...

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Detalles Bibliográficos
Autores principales: Mehrotra, Purvi, Patel, Jaymin Brakul, Ivancic, Carlie Marie, Collet, Jason Andrieu, Basile, David Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589446/
https://www.ncbi.nlm.nih.gov/pubmed/26200947
http://dx.doi.org/10.1038/ki.2015.200