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Elevated HbA(1c) levels and the accumulation of differentiated T cells in CMV(+) individuals
AIMS/HYPOTHESIS: Biological ageing of the immune system, or immunosenescence, predicts poor health and increased mortality. A hallmark of immunosenescence is the accumulation of differentiated cytotoxic T cells (CD27(−)CD45RA(+/−); or dCTLs), partially driven by infection with the cytomegalovirus (C...
Autores principales: | Rector, Jerrald L., Thomas, G. Neil, Burns, Victoria E., Dowd, Jennifer B., Herr, Raphael M., Moss, Paul A., Jarczok, Marc N., Hoffman, Kristina, Fischer, Joachim E., Bosch, Jos A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589544/ https://www.ncbi.nlm.nih.gov/pubmed/26290049 http://dx.doi.org/10.1007/s00125-015-3731-4 |
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