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Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells
Breast cancer is the most common cancer for women and is a major cause of mortality in women. Doxorubicin is a generally used chemotherapy drug for breast cancer. However, multidrug resistance of breast cancer interferes with the chemotherapy. We examined whether cucurbitacin D affects doxorubicin r...
Autores principales: | Ku, Jin Mo, Kim, Soon Re, Hong, Se Hyang, Choi, Han-Seok, Seo, Hye Sook, Shin, Yong Cheol, Ko, Seong-Gyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589559/ https://www.ncbi.nlm.nih.gov/pubmed/26169986 http://dx.doi.org/10.1007/s11010-015-2509-9 |
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