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The Attenuated Live Yellow Fever Virus 17D Infects the Thymus and Induces Thymic Transcriptional Modifications of Immunomodulatory Genes in C57BL/6 and BALB/C Mice

Thymus is involved in induction of self-tolerance in T lymphocytes, particularly due to Aire activity. In peripheral tissues, Treg cells and immunomodulatory molecules, like the major histocompatibility complex (MHC) class Ib molecules, are essential for maintenance of autotolerance during immune re...

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Detalles Bibliográficos
Autores principales:	Melo-Lima, Breno Luiz, Espósito, Danillo Lucas Alves, da Fonseca, Benedito Antônio Lopes, Figueiredo, Luiz Tadeu Moraes, Moreau, Philippe, Donadi, Eduardo Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589579/ https://www.ncbi.nlm.nih.gov/pubmed/26457200 http://dx.doi.org/10.1155/2015/503087

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