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An optogenetic system for interrogating the temporal dynamics of Akt

The dynamic activity of the serine/threonine kinase Akt is crucial for the regulation of diverse cellular functions, but the precise spatiotemporal control of its activity remains a critical issue. Herein, we present a photo-activatable Akt (PA-Akt) system based on a light-inducible protein interact...

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Detalles Bibliográficos
Autores principales: Katsura, Yoshihiro, Kubota, Hiroyuki, Kunida, Katsuyuki, Kanno, Akira, Kuroda, Shinya, Ozawa, Takeaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589684/
https://www.ncbi.nlm.nih.gov/pubmed/26423353
http://dx.doi.org/10.1038/srep14589