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Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions

Multiple attributes of the three-dimensional (3D) extracellular matrix (ECM) have been independently implicated as regulators of cell motility, including pore size, crosslink density, structural organization, and stiffness. However, these parameters cannot be independently varied within a complex 3D...

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Detalles Bibliográficos
Autores principales:	Fraley, Stephanie I., Wu, Pei-hsun, He, Lijuan, Feng, Yunfeng, Krisnamurthy, Ranjini, Longmore, Gregory D., Wirtz, Denis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589685/ https://www.ncbi.nlm.nih.gov/pubmed/26423227 http://dx.doi.org/10.1038/srep14580

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