Pediatric cancer gone viral. Part II: potential clinical application of oncolytic herpes simplex virus-1 in children

Oncolytic engineered herpes simplex viruses (HSVs) possess many biologic and functional attributes that support their use in clinical trials in children with solid tumors. Tumor cells, in an effort to escape regulatory mechanisms that would impair their growth and progression, have removed many mech...

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Detalles Bibliográficos
Autores principales: Friedman, Gregory K, Beierle, Elizabeth A, Gillespie, George Yancey, Markert, James M, Waters, Alicia M, Chen, Chun-Yu, Denton, Nicholas L, Haworth, Kellie B, Hutzen, Brian, Leddon, Jennifer L, Streby, Keri A, Wang, Pin-Yi, Cripe, Timothy P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589754/
https://www.ncbi.nlm.nih.gov/pubmed/26436134
http://dx.doi.org/10.1038/mto.2015.16

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