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The relationship between quantitative human epidermal growth factor receptor 2 gene expression by the 21-gene reverse transcriptase polymerase chain reaction assay and adjuvant trastuzumab benefit in Alliance N9831

INTRODUCTION: The N9831 trial demonstrated the efficacy of adjuvant trastuzumab for patients with human epidermal growth factor receptor 2 (HER2) locally positive tumors by protein or gene analysis. We used the 21-gene assay to examine the association of quantitative HER2 messenger RNA (mRNA) gene e...

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Detalles Bibliográficos
Autores principales: Perez, Edith A., Baehner, Frederick L., Butler, Steven M., Thompson, E. Aubrey, Dueck, Amylou C., Jamshidian, Farid, Cherbavaz, Diana, Yoshizawa, Carl, Shak, Steven, Kaufman, Peter A., Davidson, Nancy E., Gralow, Julie, Asmann, Yan W., Ballman, Karla V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589954/
https://www.ncbi.nlm.nih.gov/pubmed/26429296
http://dx.doi.org/10.1186/s13058-015-0643-7