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Plasma Chemokine signature correlates with lung goblet cell hyperplasia in smokers with and without chronic obstructive pulmonary disease
BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is characterized by lung and systemic inflammation as well as airway goblet cell hyperplasia (GCH). Mucin production is activated in part by stimulation of the epidermal growth factor (EGF) receptor pathway through neutrophils and macrophages....
Autores principales: | Kim, Victor, Cornwell, William D., Oros, Michelle, Durra, Heba, Criner, Gerard J., Rogers, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589974/ https://www.ncbi.nlm.nih.gov/pubmed/26424214 http://dx.doi.org/10.1186/s12890-015-0103-2 |
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