Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma

Emerging evidence suggests pathological and immunoregulatory functions for IgG4 antibodies and IgG4(+) B cells in inflammatory diseases and malignancies. We previously reported that IgG4 antibodies restrict activation of immune effector cell functions and impair humoral responses in melanoma. Here,...

Descripción completa

Detalles Bibliográficos
Autores principales: Karagiannis, Panagiotis, Villanova, Federica, Josephs, Debra H, Correa, Isabel, Van Hemelrijck, Mieke, Hobbs, Carl, Saul, Louise, Egbuniwe, Isioma U, Tosi, Isabella, Ilieva, Kristina M, Kent, Emma, Calonje, Eduardo, Harries, Mark, Fentiman, Ian, Taylor-Papadimitriou, Joyce, Burchell, Joy, Spicer, James F, Lacy, Katie E, Nestle, Frank O, Karagiannis, Sophia N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590000/
https://www.ncbi.nlm.nih.gov/pubmed/26451312
http://dx.doi.org/10.1080/2162402X.2015.1032492

Ejemplares similares

Ejemplares similares