Tolerance and efficacy of autologous or donor-derived T cells expressing CD19 chimeric antigen receptors in adult B-ALL with extramedullary leukemia

The engineering of T lymphocytes to express chimeric antigen receptors (CARs) aims to establish T cell-mediated tumor immunity rapidly. In this study, we conducted a pilot clinical trial of autologous or donor- derived T cells genetically modified to express a CAR targeting the B-cell antigen CD19 h...

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Detalles Bibliográficos
Autores principales: Dai, Hanren, Zhang, Wenying, Li, Xiaolei, Han, Qingwang, Guo, Yelei, Zhang, Yajing, Wang, Yao, Wang, Chunmeng, Shi, Fengxia, Zhang, Yan, Chen, Meixia, Feng, Kaichao, Wang, Quanshun, Zhu, Hongli, Fu, Xiaobing, Li, Suxia, Han, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590028/
https://www.ncbi.nlm.nih.gov/pubmed/26451310
http://dx.doi.org/10.1080/2162402X.2015.1027469

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