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Costs of HIV/AIDS treatment in Indonesia by time of treatment and stage of disease

BACKGROUND: We report an economic analysis of Human Immunodeficiency Virus (HIV) care and treatment in Indonesia to assess the options and limitations of costs reduction, improving access, and scaling up services. METHODS: We calculated the cost of providing HIV care and treatment in a main referral...

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Autores principales: Siregar, Adiatma Y. M., Tromp, Noor, Komarudin, Dindin, Wisaksana, Rudi, van Crevel, Reinout, van der Ven, Andre, Baltussen, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590258/
https://www.ncbi.nlm.nih.gov/pubmed/26424195
http://dx.doi.org/10.1186/s12913-015-1098-3
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author Siregar, Adiatma Y. M.
Tromp, Noor
Komarudin, Dindin
Wisaksana, Rudi
van Crevel, Reinout
van der Ven, Andre
Baltussen, Rob
author_facet Siregar, Adiatma Y. M.
Tromp, Noor
Komarudin, Dindin
Wisaksana, Rudi
van Crevel, Reinout
van der Ven, Andre
Baltussen, Rob
author_sort Siregar, Adiatma Y. M.
collection PubMed
description BACKGROUND: We report an economic analysis of Human Immunodeficiency Virus (HIV) care and treatment in Indonesia to assess the options and limitations of costs reduction, improving access, and scaling up services. METHODS: We calculated the cost of providing HIV care and treatment in a main referral hospital in West Java, Indonesia from 2008 to 2010, differentiated by initiation of treatment at different CD4 cell count levels (0–50, 50–100, 100–150, 150–200, and >200 cells/mm(3)); time of treatment; HIV care and opportunistic infections cost components; and the costs of patients for seeking and undergoing care. DISCUSSION: Before antiretroviral treatment (ART) initiation, costs were dominated by laboratory tests (>65 %), and after initiation, by antiretroviral drugs (≥60 %). Average treatment costs per patient decreased with time on treatment (e.g. from US$580 per patient in the first 6 month to US$473 per patient in months 19–24 for those with CD4 cell counts under 50 cells/mm(3)). Higher CD4 cell counts at initiation resulted in lower laboratory and opportunistic infection treatment costs. Transportation cost dominated the costs of patients for seeking and undergoing care (>40 %). CONCLUSIONS: Costs of providing ART are highest during the early phase of treatment. Costs reductions can potentially be realized by early treatment initiation and applying alternative laboratory tests with caution. Scaling up ART at the community level in certain high prevalence settings may improve early uptake, adherence, and reduce transportation costs.
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spelling pubmed-45902582015-10-02 Costs of HIV/AIDS treatment in Indonesia by time of treatment and stage of disease Siregar, Adiatma Y. M. Tromp, Noor Komarudin, Dindin Wisaksana, Rudi van Crevel, Reinout van der Ven, Andre Baltussen, Rob BMC Health Serv Res Research Article BACKGROUND: We report an economic analysis of Human Immunodeficiency Virus (HIV) care and treatment in Indonesia to assess the options and limitations of costs reduction, improving access, and scaling up services. METHODS: We calculated the cost of providing HIV care and treatment in a main referral hospital in West Java, Indonesia from 2008 to 2010, differentiated by initiation of treatment at different CD4 cell count levels (0–50, 50–100, 100–150, 150–200, and >200 cells/mm(3)); time of treatment; HIV care and opportunistic infections cost components; and the costs of patients for seeking and undergoing care. DISCUSSION: Before antiretroviral treatment (ART) initiation, costs were dominated by laboratory tests (>65 %), and after initiation, by antiretroviral drugs (≥60 %). Average treatment costs per patient decreased with time on treatment (e.g. from US$580 per patient in the first 6 month to US$473 per patient in months 19–24 for those with CD4 cell counts under 50 cells/mm(3)). Higher CD4 cell counts at initiation resulted in lower laboratory and opportunistic infection treatment costs. Transportation cost dominated the costs of patients for seeking and undergoing care (>40 %). CONCLUSIONS: Costs of providing ART are highest during the early phase of treatment. Costs reductions can potentially be realized by early treatment initiation and applying alternative laboratory tests with caution. Scaling up ART at the community level in certain high prevalence settings may improve early uptake, adherence, and reduce transportation costs. BioMed Central 2015-09-30 /pmc/articles/PMC4590258/ /pubmed/26424195 http://dx.doi.org/10.1186/s12913-015-1098-3 Text en © Siregar et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Siregar, Adiatma Y. M.
Tromp, Noor
Komarudin, Dindin
Wisaksana, Rudi
van Crevel, Reinout
van der Ven, Andre
Baltussen, Rob
Costs of HIV/AIDS treatment in Indonesia by time of treatment and stage of disease
title Costs of HIV/AIDS treatment in Indonesia by time of treatment and stage of disease
title_full Costs of HIV/AIDS treatment in Indonesia by time of treatment and stage of disease
title_fullStr Costs of HIV/AIDS treatment in Indonesia by time of treatment and stage of disease
title_full_unstemmed Costs of HIV/AIDS treatment in Indonesia by time of treatment and stage of disease
title_short Costs of HIV/AIDS treatment in Indonesia by time of treatment and stage of disease
title_sort costs of hiv/aids treatment in indonesia by time of treatment and stage of disease
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590258/
https://www.ncbi.nlm.nih.gov/pubmed/26424195
http://dx.doi.org/10.1186/s12913-015-1098-3
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