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Enhancing production of ergosterol in Pichia pastoris GS115 by over-expression of 3-hydroxy-3-methylglutaryl CoA reductase from Glycyrrhiza uralensis

The rate-limiting enzyme in the mevalonic acid (MVA) pathway which can lead to triterpenoid saponin glycyrrhizic acid (GA) is 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR). In order to reveal the effect of copy number variation in the HMGR gene on the MVA pathway, the HMGR gene from Glycyrrhiza ur...

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Detalles Bibliográficos
Autores principales:	Liu, Ying, Zhu, Xiaoqing, Li, Wendong, Wen, Hao, Gao, Ya, Liu, Yong, Liu, Chunsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590296/ https://www.ncbi.nlm.nih.gov/pubmed/26579379 http://dx.doi.org/10.1016/j.apsb.2014.02.007

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