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Chamaejasmin B exerts anti-MDR effect in vitro and in vivo via initiating mitochondria-dependant intrinsic apoptosis pathway

Multidrug resistance (MDR) is the main obstacle limiting the efficacy of cancer chemotherapy. Looking for novel anti-MDR agents is an important way to conquer cancer drug resistance. We recently established that chamaejasmin B (CHB), a natural biflavone from Stellera chamaejasme L., is the major act...

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Detalles Bibliográficos
Autores principales: Wang, Ya Jie, Li, Qi, Xiao, Hong Bin, Li, Yu Jie, Yang, Qing, Kan, Xiao Xi, Chen, Ying, Liu, Xiao Ni, Weng, Xiao Gang, Chen, Xi, Cai, Wei Yan, Guo, Yan, Huang, He Fei, Zhu, Xiao Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590417/
https://www.ncbi.nlm.nih.gov/pubmed/26445529
http://dx.doi.org/10.2147/DDDT.S89392

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