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Chamaejasmin B exerts anti-MDR effect in vitro and in vivo via initiating mitochondria-dependant intrinsic apoptosis pathway
Multidrug resistance (MDR) is the main obstacle limiting the efficacy of cancer chemotherapy. Looking for novel anti-MDR agents is an important way to conquer cancer drug resistance. We recently established that chamaejasmin B (CHB), a natural biflavone from Stellera chamaejasme L., is the major act...
Autores principales: | Wang, Ya Jie, Li, Qi, Xiao, Hong Bin, Li, Yu Jie, Yang, Qing, Kan, Xiao Xi, Chen, Ying, Liu, Xiao Ni, Weng, Xiao Gang, Chen, Xi, Cai, Wei Yan, Guo, Yan, Huang, He Fei, Zhu, Xiao Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590417/ https://www.ncbi.nlm.nih.gov/pubmed/26445529 http://dx.doi.org/10.2147/DDDT.S89392 |
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