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Bioinspired genotype–phenotype linkages: mimicking cellular compartmentalization for the engineering of functional proteins
The idea of compartmentalization of genotype and phenotype in cells is key for enabling Darwinian evolution. This contribution describes bioinspired systems that use in vitro compartments—water-in-oil droplets and gel-shell beads—for the directed evolution of functional proteins. Technologies based...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590426/ https://www.ncbi.nlm.nih.gov/pubmed/26464791 http://dx.doi.org/10.1098/rsfs.2015.0035 |