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Bioinspired genotype–phenotype linkages: mimicking cellular compartmentalization for the engineering of functional proteins

The idea of compartmentalization of genotype and phenotype in cells is key for enabling Darwinian evolution. This contribution describes bioinspired systems that use in vitro compartments—water-in-oil droplets and gel-shell beads—for the directed evolution of functional proteins. Technologies based...

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Detalles Bibliográficos
Autores principales: van Vliet, Liisa D., Colin, Pierre-Yves, Hollfelder, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590426/
https://www.ncbi.nlm.nih.gov/pubmed/26464791
http://dx.doi.org/10.1098/rsfs.2015.0035

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