Cargando…

Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain

Many essential biological processes are mediated by complex molecular machines comprising multiple subunits. Knowledge on the architecture of individual subunits and their positions within the overall multimeric complex is key to understanding the molecular mechanisms of macromolecular assemblies. T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cronin, Nora B., Yang, Jing, Zhang, Ziguo, Kulkarni, Kiran, Chang, Leifu, Yamano, Hiroyuki, Barford, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590430/ https://www.ncbi.nlm.nih.gov/pubmed/26343760 http://dx.doi.org/10.1016/j.jmb.2015.08.023

Ejemplares similares

The Four Canonical TPR Subunits of Human APC/C Form Related Homo-Dimeric Structures and Stack in Parallel to Form a TPR Suprahelix()
por: Zhang, Ziguo, et al.
Publicado: (2013)

Molecular basis of APC/C regulation by the spindle assembly checkpoint
por: Alfieri, Claudio, et al.
Publicado: (2016)

Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation
por: Yatskevich, Stanislau, et al.
Publicado: (2021)

Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor
por: da Fonseca, Paula C.A., et al.
Publicado: (2010)

Insights into Degron Recognition by APC/C Coactivators from the Structure of an Acm1-Cdh1 Complex
por: He, Jun, et al.
Publicado: (2013)

APC/C: current understanding and future perspectives
por: Yamano, Hiroyuki
Publicado: (2019)

PP2A‐B56 binds to Apc1 and promotes Cdc20 association with the APC/C ubiquitin ligase in mitosis
por: Fujimitsu, Kazuyuki, et al.
Publicado: (2019)

The importance of APC
por: Ablamunits, Vitaly
Publicado: (2005)

Cancer Stemness in Apc- vs. Apc/KRAS-Driven Intestinal Tumorigenesis
por: Ghazvini, Mehrnaz, et al.
Publicado: (2013)

Dynamic regulation of mitotic ubiquitin ligase APC/C by coordinated Plx1 kinase and PP2A phosphatase action on a flexible Apc1 loop
por: Fujimitsu, Kazuyuki, et al.
Publicado: (2021)

APC proteolysis not overdone
por: LeBrasseur, Nicole
Publicado: (2005)

Polo meets the APC
por: Wells, William A.
Publicado: (2002)

The APC–tumor connection
por: LeBrasseur, Nicole
Publicado: (2003)

Epithelial cells as APCs
por: LeBrasseur, Nicole
Publicado: (2008)

APC's order of business
por: LeBrasseur, Nicole
Publicado: (2006)

Where is APC going?
por: Mimori-Kiyosue, Yuko, et al.
Publicado: (2001)

lemmingA encodes the Apc11 subunit of the APC/C in Drosophila melanogaster that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2
por: Nagy, Olga, et al.
Publicado: (2012)

Polarizing T and B Cell Responses by APC-Targeted Subunit Vaccines
por: Grødeland, Gunnveig, et al.
Publicado: (2015)

Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C)
por: Alfieri, Claudio, et al.
Publicado: (2017)

Administración por calidad (APC)
por: Sosa Pulido, Demetrio
Publicado: (1991)

Inke Näthke: The ABCs of APC
por: Sedwick, Caitlin
Publicado: (2010)

Novel association of APC with intermediate filaments identified using a new versatile APC antibody
por: Wang, Yang, et al.
Publicado: (2009)

APC15 mediates CDC20 auto-ubiquitylation by APC/C(MCC) and MCC disassembly
por: Uzunova, Kristina, et al.
Publicado: (2012)

Polyanions provide selective control of APC/C interactions with the activator subunit
por: Mizrak, Arda, et al.
Publicado: (2019)

Apc-Mutant Kyoto Apc Delta (KAD) Rats Are Susceptible to 4-NQO-Induced Tongue Carcinogenesis
por: Tanaka, Takuji, et al.
Publicado: (2014)

Functional Comparison of Human Adenomatous Polyposis Coli (APC) and APC-Like in Targeting Beta-Catenin for Degradation
por: Schneikert, Jean, et al.
Publicado: (2013)

APC and MUTYH Analysis in FAP Patients: A Novel Mutation in APC Gene and Genotype-Phenotype Correlation
por: D’Elia, Giovanna, et al.
Publicado: (2018)

Deletion of APC7 or APC16 Allows Proliferation of Human Cells without the Spindle Assembly Checkpoint
por: Wild, Thomas, et al.
Publicado: (2018)

Article Processing Charges and OpenAPC
por: Wagner, Alexander
Publicado: (2017)

APC ain't always necessary for axons
por: Williams, Ruth
Publicado: (2008)

Introduction of APCs in J. Young Pharm.
por: Mueen, Ahmed KK
Publicado: (2012)

APC Promoter Methylation in Gastrointestinal Cancer
por: Zhu, Lila, et al.
Publicado: (2021)

Regulation of APC/C(Cdc20) activity by RASSF1A–APC/C(Cdc20) circuitry
por: Chow, C, et al.
Publicado: (2012)

Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells
por: King, Lauren E., et al.
Publicado: (2016)

Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium
por: Daly, C S, et al.
Publicado: (2017)

APC/C(CDC20) and APC/C play pivotal roles in the process of embryonic development in Artemia sinica
por: Zhang, Mengchen, et al.
Publicado: (2016)

Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C
por: Garvanska, Dimitriya H., et al.
Publicado: (2016)

Advanced Practice Clinician (APC) Fellowships:: A Strategic Approach to a High-Quality, Stable APC Workforce
por: Maxwell, Lisa, et al.
Publicado: (2020)

The APC/C targets the Cep152–Cep63 complex at the centrosome to regulate mitotic spindle assembly
por: Tischer, Thomas, et al.
Publicado: (2022)

METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N(6)-methyladenosine-dependent YTHDF binding
por: Wang, Wei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2r43isdrls256eave63rbi63ac