Chondroitinase gene therapy improves upper limb function following cervical contusion injury

Chondroitin sulphate proteoglycans (CSPGs) are known to be important contributors to the intensely inhibitory environment that prevents tissue repair and regeneration following spinal cord injury. The bacterial enzyme chondroitinase ABC (ChABC) degrades these inhibitory molecules and has repeatedly...

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Detalles Bibliográficos
Autores principales: James, Nicholas D., Shea, Jessie, Muir, Elizabeth M., Verhaagen, Joost, Schneider, Bernard L., Bradbury, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2015
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590527/
https://www.ncbi.nlm.nih.gov/pubmed/26044197
http://dx.doi.org/10.1016/j.expneurol.2015.05.022

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