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Parkinsonian toxin-induced oxidative stress inhibits basal autophagy in astrocytes via NQO2/quinone oxidoreductase 2: Implications for neuroprotection

Oxidative stress (OS) stimulates autophagy in different cellular systems, but it remains controversial if this rule can be generalized. We have analyzed the effect of chronic OS induced by the parkinsonian toxin paraquat (PQ) on autophagy in astrocytoma cells and primary astrocytes, which represent...

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Detalles Bibliográficos
Autores principales: Janda, Elzbieta, Lascala, Antonella, Carresi, Cristina, Parafati, Maddalena, Aprigliano, Serafina, Russo, Vanessa, Savoia, Claudia, Ziviani, Elena, Musolino, Vincenzo, Morani, Federica, Isidoro, Ciro, Mollace, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590600/
https://www.ncbi.nlm.nih.gov/pubmed/26046590
http://dx.doi.org/10.1080/15548627.2015.1058683