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Single-cell analysis challenges the connection between autophagy and senescence induced by DNA damage

Autophagy and senescence have been described as central features of cell biology, but the interplay between these mechanisms remains obscure. Using a therapeutically relevant model of DNA damage-induced senescence in human glioma cells, we demonstrated that acute treatment with temozolomide induces...

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Detalles Bibliográficos
Autores principales:	Filippi-Chiela, Eduardo Cremonese, Silva, Mardja Manssur Bueno e, Thomé, Marcos Paulo, Lenz, Guido
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Basic Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590630/ https://www.ncbi.nlm.nih.gov/pubmed/25701485 http://dx.doi.org/10.1080/15548627.2015.1009795

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