Novel single-nucleotide polymorphisms in the calsequestrin-1 gene are associated with Graves’ ophthalmopathy and Hashimoto’s thyroiditis

BACKGROUND: The eye disorder associated with Graves’ disease, called Graves’ ophthalmopathy (GO), greatly reduces the quality of life in affected patients. Expression of the calsequestrin (CASQ1) protein in thyroid tissue may be the trigger for the development of eye muscle damage in patients with G...

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Detalles Bibliográficos
Autores principales: Lahooti, Hooshang, Cultrone, Daniele, Edirimanne, Senarath, Walsh, John P, Delbridge, Leigh, Cregan, Patrick, Champion, Bernard, Wall, Jack R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590686/
https://www.ncbi.nlm.nih.gov/pubmed/26445519
http://dx.doi.org/10.2147/OPTH.S87972

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