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Preparation and evaluation of sustained-release solid dispersions co-loading gastrodin with borneol as an oral brain-targeting enhancer
Borneol is a traditional Chinese medicine that can promote drug absorption from the gastrointestinal tract and distribution to the brain. However, stomach irritation may occur when high doses of borneol are used. In the present work, gastrodin, the main bioactive ingredient of the traditional Chines...
Autores principales: | Cai, Zheng, Lei, Xiaolu, Lin, Zhufen, Zhao, Jie, Wu, Feizhen, Yang, Zhaoxiang, Pu, Junxue, Liu, Zhongqiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590720/ https://www.ncbi.nlm.nih.gov/pubmed/26579369 http://dx.doi.org/10.1016/j.apsb.2013.12.012 |
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