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Role of mucoadhesive polymers in enhancing delivery of nimodipine microemulsion to brain via intranasal route

Intranasal drug administration is receiving increased attention as a delivery method for bypassing the blood–brain barrier and rapidly targeting therapeutics to the CNS. However, rapid mucociliary clearance in the nasal cavity is a major hurdle. The purpose of this study was to evaluate the effect o...

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Detalles Bibliográficos
Autores principales: Pathak, Rudree, Dash, Ranjeet Prasad, Misra, Manju, Nivsarkar, Manish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590727/
https://www.ncbi.nlm.nih.gov/pubmed/26579378
http://dx.doi.org/10.1016/j.apsb.2014.02.002