Three-dimensional DEM–CFD analysis of air-flow-induced detachment of API particles from carrier particles in dry powder inhalers

Air flow and particle–particle/wall impacts are considered as two primary dispersion mechanisms for dry powder inhalers (DPIs). Hence, an understanding of these mechanisms is critical for the development of DPIs. In this study, a coupled DEM–CFD (discrete element method–computational fluid dynamics)...

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Detalles Bibliográficos
Autores principales: Yang, Jiecheng, Wu, Chuan-Yu, Adams, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590728/
https://www.ncbi.nlm.nih.gov/pubmed/26579364
http://dx.doi.org/10.1016/j.apsb.2013.11.003

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