Solubility Enhancement of Raloxifene Using Inclusion Complexes and Cogrinding Method

The objective of the present work was to enhance the solubility and dissolution of practically water-insoluble drug raloxifene HCl (RLX), for the same two approaches that were used. In the first approach, drug was kneaded with hydroxypropyl-β-cyclodextrin (HPβCD), and in the second one drug was cogr...

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Detalles Bibliográficos
Autores principales: Patil, Payal H., Belgamwar, Veena S., Patil, Pratibha R., Surana, Sanjay J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590818/
https://www.ncbi.nlm.nih.gov/pubmed/26555984
http://dx.doi.org/10.1155/2013/527380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590818/
https://www.ncbi.nlm.nih.gov/pubmed/26555984
http://dx.doi.org/10.1155/2013/527380

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