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p21(WAF1/CIP1) Expression is Differentially Regulated by Metformin and Rapamycin
The mammalian target of rapamycin (mTOR) pathway plays an important role in the development of diabetic nephropathy and other age-related diseases. One of the features of DN is the elevated expression of p21(WAF1/CIP1). However, the importance of the mTOR signalling pathway in p21 regulation is poor...
Autores principales: | Molnar, Zoltan, Millward, Ann B., Tse, Wai, Demaine, Andrew G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590942/ https://www.ncbi.nlm.nih.gov/pubmed/26464852 http://dx.doi.org/10.1155/2014/327640 |
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