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Functional Impact and Evolution of a Novel Human Polymorphic Inversion That Disrupts a Gene and Creates a Fusion Transcript
Despite many years of study into inversions, very little is known about their functional consequences, especially in humans. A common hypothesis is that the selective value of inversions stems in part from their effects on nearby genes, although evidence of this in natural populations is almost none...
Autores principales: | Puig, Marta, Castellano, David, Pantano, Lorena, Giner-Delgado, Carla, Izquierdo, David, Gayà-Vidal, Magdalena, Lucas-Lledó, José Ignacio, Esko, Tõnu, Terao, Chikashi, Matsuda, Fumihiko, Cáceres, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591017/ https://www.ncbi.nlm.nih.gov/pubmed/26427027 http://dx.doi.org/10.1371/journal.pgen.1005495 |
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