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Inhibitory Effects of Green Tea and (–)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein

Green tea catechins inhibit the function of organic anion transporting polypeptides (OATPs) that mediate the uptake of a diverse group of drugs and endogenous compounds into cells. The present study was aimed at investigating the effect of green tea and its most abundant catechin epigallocatechin ga...

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Detalles Bibliográficos
Autores principales: Knop, Jana, Misaka, Shingen, Singer, Katrin, Hoier, Eva, Müller, Fabian, Glaeser, Hartmut, König, Jörg, Fromm, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591125/
https://www.ncbi.nlm.nih.gov/pubmed/26426900
http://dx.doi.org/10.1371/journal.pone.0139370