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Inhibitory Effects of Green Tea and (–)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein
Green tea catechins inhibit the function of organic anion transporting polypeptides (OATPs) that mediate the uptake of a diverse group of drugs and endogenous compounds into cells. The present study was aimed at investigating the effect of green tea and its most abundant catechin epigallocatechin ga...
Autores principales: | Knop, Jana, Misaka, Shingen, Singer, Katrin, Hoier, Eva, Müller, Fabian, Glaeser, Hartmut, König, Jörg, Fromm, Martin F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591125/ https://www.ncbi.nlm.nih.gov/pubmed/26426900 http://dx.doi.org/10.1371/journal.pone.0139370 |
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