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Dissecting Fission Yeast Shelterin Interactions via MICro-MS Links Disruption of Shelterin Bridge to Tumorigenesis
Shelterin, a six-member complex, protects telomeres from nucleolytic attack and regulates their elongation by telomerase. Here, we have developed a strategy, called MICro-MS (Mapping Interfaces via Crosslinking-Mass Spectrometry), that combines crosslinking-mass spectrometry and phylogenetic analysi...
Autores principales: | Liu, Jinqiang, Yu, Clinton, Hu, Xichan, Kim, Jin-Kwang, Bierma, Jan C., Jun, Hyun-Ik, Rychnovsky, Scott D., Huang, Lan, Qiao, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591219/ https://www.ncbi.nlm.nih.gov/pubmed/26365187 http://dx.doi.org/10.1016/j.celrep.2015.08.043 |
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