Cargando…
Prion Protein Does Not Confer Resistance to Hippocampus-Derived Zpl Cells against the Toxic Effects of Cu(2+), Mn(2+), Zn(2+) and Co(2+) Not Supporting a General Protective Role for PrP in Transition Metal Induced Toxicity
The interactions of transition metals with the prion protein (PrP) are well-documented and characterized, however, there is no consensus on their role in either the physiology of PrP or PrP-related neurodegenerative disorders. PrP has been reported to protect cells from the toxic stimuli of metals....
Autores principales: | Cingaram, Pradeep Kumar Reddy, Nyeste, Antal, Dondapati, Divya Teja, Fodor, Elfrieda, Welker, Ervin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591282/ https://www.ncbi.nlm.nih.gov/pubmed/26426582 http://dx.doi.org/10.1371/journal.pone.0139219 |
Ejemplares similares
-
Membrane Domain Localization and Interaction of the Prion-Family Proteins, Prion and Shadoo with Calnexin
por: Dondapati, Divya Teja, et al.
Publicado: (2021) -
A programmer's guide to ZPL
por: Snyder, Lawrence, et al.
Publicado: (1999) -
A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity
por: Bardelli, Marco, et al.
Publicado: (2018) -
The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells
por: Nyeste, Antal, et al.
Publicado: (2016) -
The Structure of PrP(Sc) Prions
por: Wille, Holger, et al.
Publicado: (2018)