Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism

Here, we report the draft genome sequences of three actinobacterial isolates, Micromonospora sp. RV43, Rubrobacter sp. RV113, and Nocardiopsis sp. RV163 that had previously been isolated from Mediterranean sponges. The draft genomes were analyzed for the presence of gene clusters indicative of secon...

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Detalles Bibliográficos
Autores principales: Horn, Hannes, Hentschel, Ute, Abdelmohsen, Usama Ramadan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591302/
https://www.ncbi.nlm.nih.gov/pubmed/26430030
http://dx.doi.org/10.1128/genomeA.01106-15
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author Horn, Hannes
Hentschel, Ute
Abdelmohsen, Usama Ramadan
author_facet Horn, Hannes
Hentschel, Ute
Abdelmohsen, Usama Ramadan
author_sort Horn, Hannes
collection PubMed
description Here, we report the draft genome sequences of three actinobacterial isolates, Micromonospora sp. RV43, Rubrobacter sp. RV113, and Nocardiopsis sp. RV163 that had previously been isolated from Mediterranean sponges. The draft genomes were analyzed for the presence of gene clusters indicative of secondary metabolism using antiSMASH 3.0 and NapDos pipelines. Our findings demonstrated the chemical richness of sponge-associated actinomycetes and the efficacy of genome mining in exploring the genomic potential of sponge-derived actinomycetes.
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spelling pubmed-45913022015-10-08 Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism Horn, Hannes Hentschel, Ute Abdelmohsen, Usama Ramadan Genome Announc Prokaryotes Here, we report the draft genome sequences of three actinobacterial isolates, Micromonospora sp. RV43, Rubrobacter sp. RV113, and Nocardiopsis sp. RV163 that had previously been isolated from Mediterranean sponges. The draft genomes were analyzed for the presence of gene clusters indicative of secondary metabolism using antiSMASH 3.0 and NapDos pipelines. Our findings demonstrated the chemical richness of sponge-associated actinomycetes and the efficacy of genome mining in exploring the genomic potential of sponge-derived actinomycetes. American Society for Microbiology 2015-10-01 /pmc/articles/PMC4591302/ /pubmed/26430030 http://dx.doi.org/10.1128/genomeA.01106-15 Text en Copyright © 2015 Horn et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Prokaryotes
Horn, Hannes
Hentschel, Ute
Abdelmohsen, Usama Ramadan
Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism
title Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism
title_full Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism
title_fullStr Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism
title_full_unstemmed Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism
title_short Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism
title_sort mining genomes of three marine sponge-associated actinobacterial isolates for secondary metabolism
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591302/
https://www.ncbi.nlm.nih.gov/pubmed/26430030
http://dx.doi.org/10.1128/genomeA.01106-15
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