Genome Comparison of an Ancestral Isolate and a Modern Isolate of Mycobacterium tuberculosis of the Beijing Lineage from São Paulo, Brazil

Mycobacterium tuberculosis of the Bejing subtype (MtbB) is transmitted efficiently in high burden countries for this genotype. A higher virulence was associated with isolates of the “modern” Beijing genotype sub-lineages when compared to “ancient” ones. Here, we report the full genomes of the strain...

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Detalles Bibliográficos
Autores principales: Gomes, Lia Lima, Marin, Michel Abanto, Lasunskaia, Elena, Vasconcellos, Sidra Ezidio Gonçalves, de Araujo, Marcelo Emanuel Ivens, de Miranda, Antonio Basílio, Suffys, Philip Noel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591316/
https://www.ncbi.nlm.nih.gov/pubmed/26430044
http://dx.doi.org/10.1128/genomeA.01129-15
Descripción
Sumario:Mycobacterium tuberculosis of the Bejing subtype (MtbB) is transmitted efficiently in high burden countries for this genotype. A higher virulence was associated with isolates of the “modern” Beijing genotype sub-lineages when compared to “ancient” ones. Here, we report the full genomes of the strain representing these two genotypes from Brazil, a country with a low incidence of MtbB.

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