Acute Liver Failure in a Pediatric Patient with Congenital Dysery-Thropoietic Anemia Type I Treated with Deferasirox

Congenital dyserythropoietic anemias (CDA) represent a heterogeneous group of disorders characterized by morphological abnormalities of erythroid precursor cells and various degrees of hemolysis. Iron overload is a result of continuous hemolysis and recurrent transfusions. It is treated with iron ch...

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Detalles Bibliográficos
Autores principales: Ling, Galina, Pinsk, Vered, Golan-Tripto, Inbal, Ling, Eduard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591501/
https://www.ncbi.nlm.nih.gov/pubmed/26487935
http://dx.doi.org/10.4081/hr.2015.5987
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author Ling, Galina
Pinsk, Vered
Golan-Tripto, Inbal
Ling, Eduard
author_facet Ling, Galina
Pinsk, Vered
Golan-Tripto, Inbal
Ling, Eduard
author_sort Ling, Galina
collection PubMed
description Congenital dyserythropoietic anemias (CDA) represent a heterogeneous group of disorders characterized by morphological abnormalities of erythroid precursor cells and various degrees of hemolysis. Iron overload is a result of continuous hemolysis and recurrent transfusions. It is treated with iron chelators, including deferasirox. We present here a case of acute liver failure in a 12 years old girl with CDA type I treated with deferasirox and discuss the approach to treatment.
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spelling pubmed-45915012015-10-20 Acute Liver Failure in a Pediatric Patient with Congenital Dysery-Thropoietic Anemia Type I Treated with Deferasirox Ling, Galina Pinsk, Vered Golan-Tripto, Inbal Ling, Eduard Hematol Rep Case Report Congenital dyserythropoietic anemias (CDA) represent a heterogeneous group of disorders characterized by morphological abnormalities of erythroid precursor cells and various degrees of hemolysis. Iron overload is a result of continuous hemolysis and recurrent transfusions. It is treated with iron chelators, including deferasirox. We present here a case of acute liver failure in a 12 years old girl with CDA type I treated with deferasirox and discuss the approach to treatment. PAGEPress Publications, Pavia, Italy 2015-09-23 /pmc/articles/PMC4591501/ /pubmed/26487935 http://dx.doi.org/10.4081/hr.2015.5987 Text en ©Copyright G. Ling et al. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ling, Galina
Pinsk, Vered
Golan-Tripto, Inbal
Ling, Eduard
Acute Liver Failure in a Pediatric Patient with Congenital Dysery-Thropoietic Anemia Type I Treated with Deferasirox
title Acute Liver Failure in a Pediatric Patient with Congenital Dysery-Thropoietic Anemia Type I Treated with Deferasirox
title_full Acute Liver Failure in a Pediatric Patient with Congenital Dysery-Thropoietic Anemia Type I Treated with Deferasirox
title_fullStr Acute Liver Failure in a Pediatric Patient with Congenital Dysery-Thropoietic Anemia Type I Treated with Deferasirox
title_full_unstemmed Acute Liver Failure in a Pediatric Patient with Congenital Dysery-Thropoietic Anemia Type I Treated with Deferasirox
title_short Acute Liver Failure in a Pediatric Patient with Congenital Dysery-Thropoietic Anemia Type I Treated with Deferasirox
title_sort acute liver failure in a pediatric patient with congenital dysery-thropoietic anemia type i treated with deferasirox
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591501/
https://www.ncbi.nlm.nih.gov/pubmed/26487935
http://dx.doi.org/10.4081/hr.2015.5987
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