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Epidermal growth factor–stimulated Akt phosphorylation requires clathrin or ErbB2 but not receptor endocytosis

Epidermal growth factor (EGF) binding to its receptor (EGFR) activates several signaling intermediates, including Akt, leading to control of cell survival and metabolism. Concomitantly, ligand-bound EGFR is incorporated into clathrin-coated pits—membrane structures containing clathrin and other prot...

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Detalles Bibliográficos
Autores principales:	Garay, Camilo, Judge, Gurjeet, Lucarelli, Stefanie, Bautista, Stephen, Pandey, Rohan, Singh, Tanveer, Antonescu, Costin N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591694/ https://www.ncbi.nlm.nih.gov/pubmed/26246598 http://dx.doi.org/10.1091/mbc.E14-09-1412

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