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Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study

BACKGROUND AND PURPOSE OF THE STUDY: Renal injury and dysfunction are serious complications after major surgery, which may lead to increased morbidity and mortality. The objective of our study was to identify the possible risk factors for renal dysfunction after total hip joint replacement surgery....

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Autores principales: Hassan, Basim Kamil, Sahlström, Arne, Dessau, Ram Benny Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591710/
https://www.ncbi.nlm.nih.gov/pubmed/26429725
http://dx.doi.org/10.1186/s13018-015-0299-0
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author Hassan, Basim Kamil
Sahlström, Arne
Dessau, Ram Benny Christian
author_facet Hassan, Basim Kamil
Sahlström, Arne
Dessau, Ram Benny Christian
author_sort Hassan, Basim Kamil
collection PubMed
description BACKGROUND AND PURPOSE OF THE STUDY: Renal injury and dysfunction are serious complications after major surgery, which may lead to increased morbidity and mortality. The objective of our study was to identify the possible risk factors for renal dysfunction after total hip joint replacement surgery. METHODS: A retrospective study was conducted among 599 consecutive primary hip joint replacements performed between January 2011 and December 2013. According to the RIFLE criteria, increased postoperative serum creatinine was considered indicative of postoperative renal injury. The Welch two-sample test, chi-square test, and Fisher exact test were used for statistical analysis. RESULTS: Eighty-one patients (13.8 %) had significant moderate or severe postoperative renal dysfunction in which 10 patients (1.7 %) acquired severe and permanent renal impairment. CONCLUSION: We identified advanced age, hypertension, general anesthesia, high ASA scores, low intra-operative systolic BP, and prophylactic dicloxacillin as significant risk factors. Low baseline systolic BP, low baseline diastolic blood pressure, and hip fracture diagnosis were independent risk factors for postoperative increase in serum creatinine. Smoking, diabetes mellitus, high BMI, gender, and duration of surgery were not identified as significant risk factors.
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spelling pubmed-45917102015-10-03 Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study Hassan, Basim Kamil Sahlström, Arne Dessau, Ram Benny Christian J Orthop Surg Res Research Article BACKGROUND AND PURPOSE OF THE STUDY: Renal injury and dysfunction are serious complications after major surgery, which may lead to increased morbidity and mortality. The objective of our study was to identify the possible risk factors for renal dysfunction after total hip joint replacement surgery. METHODS: A retrospective study was conducted among 599 consecutive primary hip joint replacements performed between January 2011 and December 2013. According to the RIFLE criteria, increased postoperative serum creatinine was considered indicative of postoperative renal injury. The Welch two-sample test, chi-square test, and Fisher exact test were used for statistical analysis. RESULTS: Eighty-one patients (13.8 %) had significant moderate or severe postoperative renal dysfunction in which 10 patients (1.7 %) acquired severe and permanent renal impairment. CONCLUSION: We identified advanced age, hypertension, general anesthesia, high ASA scores, low intra-operative systolic BP, and prophylactic dicloxacillin as significant risk factors. Low baseline systolic BP, low baseline diastolic blood pressure, and hip fracture diagnosis were independent risk factors for postoperative increase in serum creatinine. Smoking, diabetes mellitus, high BMI, gender, and duration of surgery were not identified as significant risk factors. BioMed Central 2015-10-01 /pmc/articles/PMC4591710/ /pubmed/26429725 http://dx.doi.org/10.1186/s13018-015-0299-0 Text en © Hassan et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Hassan, Basim Kamil
Sahlström, Arne
Dessau, Ram Benny Christian
Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study
title Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study
title_full Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study
title_fullStr Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study
title_full_unstemmed Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study
title_short Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study
title_sort risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591710/
https://www.ncbi.nlm.nih.gov/pubmed/26429725
http://dx.doi.org/10.1186/s13018-015-0299-0
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