Cargando…
Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study
BACKGROUND AND PURPOSE OF THE STUDY: Renal injury and dysfunction are serious complications after major surgery, which may lead to increased morbidity and mortality. The objective of our study was to identify the possible risk factors for renal dysfunction after total hip joint replacement surgery....
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591710/ https://www.ncbi.nlm.nih.gov/pubmed/26429725 http://dx.doi.org/10.1186/s13018-015-0299-0 |
_version_ | 1782393124523343872 |
---|---|
author | Hassan, Basim Kamil Sahlström, Arne Dessau, Ram Benny Christian |
author_facet | Hassan, Basim Kamil Sahlström, Arne Dessau, Ram Benny Christian |
author_sort | Hassan, Basim Kamil |
collection | PubMed |
description | BACKGROUND AND PURPOSE OF THE STUDY: Renal injury and dysfunction are serious complications after major surgery, which may lead to increased morbidity and mortality. The objective of our study was to identify the possible risk factors for renal dysfunction after total hip joint replacement surgery. METHODS: A retrospective study was conducted among 599 consecutive primary hip joint replacements performed between January 2011 and December 2013. According to the RIFLE criteria, increased postoperative serum creatinine was considered indicative of postoperative renal injury. The Welch two-sample test, chi-square test, and Fisher exact test were used for statistical analysis. RESULTS: Eighty-one patients (13.8 %) had significant moderate or severe postoperative renal dysfunction in which 10 patients (1.7 %) acquired severe and permanent renal impairment. CONCLUSION: We identified advanced age, hypertension, general anesthesia, high ASA scores, low intra-operative systolic BP, and prophylactic dicloxacillin as significant risk factors. Low baseline systolic BP, low baseline diastolic blood pressure, and hip fracture diagnosis were independent risk factors for postoperative increase in serum creatinine. Smoking, diabetes mellitus, high BMI, gender, and duration of surgery were not identified as significant risk factors. |
format | Online Article Text |
id | pubmed-4591710 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-45917102015-10-03 Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study Hassan, Basim Kamil Sahlström, Arne Dessau, Ram Benny Christian J Orthop Surg Res Research Article BACKGROUND AND PURPOSE OF THE STUDY: Renal injury and dysfunction are serious complications after major surgery, which may lead to increased morbidity and mortality. The objective of our study was to identify the possible risk factors for renal dysfunction after total hip joint replacement surgery. METHODS: A retrospective study was conducted among 599 consecutive primary hip joint replacements performed between January 2011 and December 2013. According to the RIFLE criteria, increased postoperative serum creatinine was considered indicative of postoperative renal injury. The Welch two-sample test, chi-square test, and Fisher exact test were used for statistical analysis. RESULTS: Eighty-one patients (13.8 %) had significant moderate or severe postoperative renal dysfunction in which 10 patients (1.7 %) acquired severe and permanent renal impairment. CONCLUSION: We identified advanced age, hypertension, general anesthesia, high ASA scores, low intra-operative systolic BP, and prophylactic dicloxacillin as significant risk factors. Low baseline systolic BP, low baseline diastolic blood pressure, and hip fracture diagnosis were independent risk factors for postoperative increase in serum creatinine. Smoking, diabetes mellitus, high BMI, gender, and duration of surgery were not identified as significant risk factors. BioMed Central 2015-10-01 /pmc/articles/PMC4591710/ /pubmed/26429725 http://dx.doi.org/10.1186/s13018-015-0299-0 Text en © Hassan et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Hassan, Basim Kamil Sahlström, Arne Dessau, Ram Benny Christian Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study |
title | Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study |
title_full | Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study |
title_fullStr | Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study |
title_full_unstemmed | Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study |
title_short | Risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study |
title_sort | risk factors for renal dysfunction after total hip joint replacement; a retrospective cohort study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591710/ https://www.ncbi.nlm.nih.gov/pubmed/26429725 http://dx.doi.org/10.1186/s13018-015-0299-0 |
work_keys_str_mv | AT hassanbasimkamil riskfactorsforrenaldysfunctionaftertotalhipjointreplacementaretrospectivecohortstudy AT sahlstromarne riskfactorsforrenaldysfunctionaftertotalhipjointreplacementaretrospectivecohortstudy AT dessaurambennychristian riskfactorsforrenaldysfunctionaftertotalhipjointreplacementaretrospectivecohortstudy |