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Declining trend of Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant alleles after the withdrawal of Sulfadoxine-Pyrimethamine in North Western Ethiopia

Antimalarial drug resistance is one of the major challenges in global efforts of malaria control and elimination. In 1998, chloroquine was abandoned and replaced with sulfadoxine/pyrimethamine, which in turn was replaced with artemether/lumefantrine for the treatment of uncomplicated falciparum mala...

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Detalles Bibliográficos
Autores principales:	Tessema, Sofonias K., Kassa, Moges, Kebede, Amha, Mohammed, Hussein, Leta, Gemechu Tadesse, Woyessa, Adugna, Guma, Geremew Tasew, Petros, Beyene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591967/ https://www.ncbi.nlm.nih.gov/pubmed/26431464 http://dx.doi.org/10.1371/journal.pone.0126943

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