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Increased Duration of Heating Boosts Local Drug Deposition during Radiofrequency Ablation in Combination with Thermally Sensitive Liposomes (ThermoDox) in a Porcine Model

INTRODUCTION: Radiofrequency ablation (RFA) is used for the local treatment of liver cancer. RFA is effective for small (<3cm) tumors, but for tumors > 3 cm, there is a tendency to leave viable tumor cells in the margins or clefts of overlapping ablation zones. This increases the possibility o...

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Detalles Bibliográficos
Autores principales: Swenson, Christine E., Haemmerich, Dieter, Maul, Donald H., Knox, Bridget, Ehrhart, Nicole, Reed, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592068/
https://www.ncbi.nlm.nih.gov/pubmed/26431204
http://dx.doi.org/10.1371/journal.pone.0139752